• 10 Best Mosquito Bite Creams in 2022 (Dermatologist-Reviewed) 1
  • 10 Best Mosquito Bite Creams in 2022 (Dermatologist-Reviewed) 2
  • 10 Best Mosquito Bite Creams in 2022 (Dermatologist-Reviewed) 3
  • 10 Best Mosquito Bite Creams in 2022 (Dermatologist-Reviewed) 4
  • 10 Best Mosquito Bite Creams in 2022 (Dermatologist-Reviewed) 5

10 Best Mosquito Bite Creams in 2022 (Dermatologist-Reviewed)

Tired of getting bitten by mosquitoes? Searching for a way to relieve all the itching from mosquito bites? Invest in a mosquito bite cream! Mosquito bite creams are formulated with active ingredients such as hydrocortisone, lidocaine, and calamine and can help you soothe the itchy red bumps those nagging insects left behind. Many also contain soothing ingredients like aloe vera and colloidal oatmeal to keep your skin moisturized and facilitate the healing process. 


Cortizone 10's Maximum Strength is one of the best mosquito bite creams available online! It's made with one percent of hydrocortisone and can help alleviate your itching and reduce swelling. For more options, continue reading our list of favorites! If you're new to mosquito bite creams and don't know what product to choose, you can check out our buying guide reviewed by a board certified dermatologist at the end for some helpful tips. 

Experts featured in this article

Dr. Lauren Levy
  • Last updated: 05-20-2022
Table of Contents

Compare the 10 Best Mosquito Bite Creams

Image
1
Cortisone 10 1% Hydrocortisone Anti-Itch Creme With Aloe 1

Cortisone 10

2
Aveeno 1% Hydrocortisone Anti-Itch Cream 1

Aveeno

3
Benadryl  Itch Stopping Cream  1

Benadryl

4
Nature's Willow Bug Bite Balm  1

Nature's Willow

5
3M  Ultrathon Insect Repellent Lotion 1

3M

6
Gold Bond  Multi-Symptom Pain and Itch Relief Cream 1

Gold Bond

7
Proven Insect Repellent Lotion 1

Proven

8
Equate 1% Hydrocortisone Anti-Itch Cream  1

Equate

9
Caladryl  Calamine Plus Itch Reliever  1

Caladryl

10
Sallyeander No-Bite-Me  1

Sallyeander

Name

1% Hydrocortisone Anti-Itch Creme With Aloe

1% Hydrocortisone Anti-Itch Cream

Itch Stopping Cream

Bug Bite Balm

Ultrathon Insect Repellent Lotion

Multi-Symptom Pain and Itch Relief Cream

Insect Repellent Lotion

1% Hydrocortisone Anti-Itch Cream

Calamine Plus Itch Reliever

No-Bite-Me

Features

Thick Consistency and Suitable for Sensitive Skin

Great Moisturizing Relief for Irritated Skin

Relief From Bug Bites and Rashes

Provide a Cooling Sensation to Soothe Your Itchy Spots

Highly Effective in Preventing Mosquitoes

Lidocaine to Numb Pain and Itching

Keep Mosquitoes Away With This Repellent

A Moisturizing Cream That Works for All Kinds of Itching

Calamine and Pramoxine to Cool and Soothe

2-in-1 Solution for Mosquito Bites

Price$6.46$4.97$5.49$6.00$7.49$6.74$14.40$4.52$5.47$13.95
Amount2 oz. 1 oz. 1 oz. 0.5 oz. 2 oz.1.75 oz. 6 oz. 4 oz. 6 oz. 2 oz.
Formulated with Hydrocortisone 1%, aloe vera, beeswax Hydrocortisone 1%, oat kernel extract, oat kernel oilDiphenhydramine hydrochloride 1%, zinc acetate 0.1% Menthol 1%, almond oil, jojoba seed extract, lemongrass oil, sunflower oil, white willow bark extract DEET 34%Lidocaine 4%, aloe veraPicaridin 20% Hydrocortisone 1%, aloe vera Calamine 8%, pramoxine hydrochloride 1%Eugenol, essential oils of cedar, lemongrass, geranium, mint
Link

10 Best Mosquito Bite Creams

Here are our 10 best mosquito bite creams that are highly recommended by reviewers. We've ranked them based on their effectiveness in preventing mosquitoes or soothing mosquito bites. 


*Please note that these products were chosen after extensive research by mybest writers. The choices are not necessarily affiliated with or recommended by Dr. Lauren Levy unless explicitly stated so.

1

Cortisone 101% Hydrocortisone Anti-Itch Creme With Aloe

Maximum Strength

$6.46

Amount2 oz.
Formulated with Hydrocortisone 1%, aloe vera, beeswax
2

Aveeno1% Hydrocortisone Anti-Itch Cream

Maximum Strength

$4.97

Amount1 oz.
Formulated with Hydrocortisone 1%, oat kernel extract, oat kernel oil
3

Benadryl Itch Stopping Cream

Original Strength

$5.49

Amount1 oz.
Formulated with Diphenhydramine hydrochloride 1%, zinc acetate 0.1%
4

Nature's WillowBug Bite Balm

$6.00

Amount0.5 oz.
Formulated with Menthol 1%, almond oil, jojoba seed extract, lemongrass oil, sunflower oil, white willow bark extract
5

3M Ultrathon Insect Repellent Lotion

$7.49

Amount2 oz.
Formulated with DEET 34%
6

Gold Bond Multi-Symptom Pain and Itch Relief Cream

$6.74

Amount1.75 oz.
Formulated with Lidocaine 4%, aloe vera
7
Amount6 oz.
Formulated with Picaridin 20%
8

Equate1% Hydrocortisone Anti-Itch Cream

Maximum Strength

$4.52

Amount4 oz.
Formulated with Hydrocortisone 1%, aloe vera
9

Caladryl Calamine Plus Itch Reliever

$5.47

Amount6 oz.
Formulated with Calamine 8%, pramoxine hydrochloride 1%
10

SallyeanderNo-Bite-Me

$13.95

Amount2 oz.
Formulated with Eugenol, essential oils of cedar, lemongrass, geranium, mint

How to Choose a Mosquito Bite Cream - Buying Guide

To help you choose a mosquito bite cream, we created this buying guide with all the crucial points to take into consideration. Remember to take a look at the ingredient list and make sure there are effective active ingredients that help with mosquito bites! 

Look For Active Ingredients That Soothe Itching

Look For Active Ingredients That Soothe Itching

Effective anti-itch creams are usually formulated with active ingredients such as hydrocortisone, lidocaine, diphenhydramine hydrochloride, menthol, calamine, and pramoxine.


Hydrocortisone is a steroid hormone that can help alleviate inflammation caused by mosquito bites. Lidocaine and pramoxine are anesthetics and can numb your itching.

Look For Active Ingredients That Soothe Itching

Menthol is derived from mint plants and can provide a cooling sensation to the skin to reduce itchiness. Camphor and eucalyptus essential oils also have the same effects.


Calamine, a combination of zinc and iron oxides, cools the skin to relieve inflammation and itching.

Dr. Lauren Levy
Board Certified Dermatologist
Dr. Lauren Levy

Hydrocortisone is an anti-inflammatory that reduces redness, swelling, and itch. Lidocaine is a topical anesthetic that will block out the sensation of itch but will not help reduce inflammation.


I never recommend topical antihistamines like Benadryl cream. The reason is that topical antihistamines like Benadryl cream can cause allergic contact dermatitis (an itchy eczema-like skin rash), that can sensitize you to become allergic to oral Benadryl in the future. This means that you will no longer be able to take oral antihistamines like Benadryl.

Pay Attention to the Concentration of the Active Ingredient

Pay Attention to the Concentration of the Active Ingredient

The concentration of the active ingredient is another important factor to pay attention to, especially if you have sensitive skin. A cream with a low concentration of an active ingredient is less likely to trigger allergic reactions but might not give you long-lasting protection or relief from itching. 


Meanwhile, a high concentration might cause irritation to sensitive skin and might not be suitable for children. So, check the directions to make sure that the cream is suitable for you or your child. Consult with your doctor when in doubt! 


Also, some inactive ingredients in a mosquito bite cream might lead to allergic reactions. For example, fragrance ingredients have been shown to be one of the major causes of allergic contact dermatitis. So if you have fragrance sensitivity, go for an odorless cream without any fragrance ingredients. 

Pay Attention to the Concentration of the Active Ingredient

Active ingredients can lead to skin irritation, too. Those with a skin infection or who are pregnant shouldn't use hydrocortisone, as it might cause a burning sensation to the skin or even lead to redness. Many people are also allergic to essential oils like eucalyptus.


Serious side effects to mosquito bite creams are unlikely. However, if you have sensitive skin, we highly suggest talking to your doctor to make sure that the cream contains safe ingredients for you. 

Soothe Your Skin With Moisturizers

Soothe Your Skin With Moisturizers

Many effective mosquito bite creams are made with soothing and moisturizing ingredients like aloe vera, vitamin E, and colloidal oatmeal. Those ingredients not only promote healing but also calm skin inflammation and moisturize


Keep in mind, however, that they only provide additional benefits. Active ingredients are the ones that truly relieve itching! 

Dr. Lauren Levy
Board Certified Dermatologist
Dr. Lauren Levy

Dry skin, known as xerosis, can trigger itch. Having hydrated skin makes you less likely to itch. Look for products that contain ceramides, hyaluronic acid, and glycerin. If your skin is very dry choose an emollient-based moisturizer (one that is oil-based, like Aquaphor or Vaseline) that locks in hydration.

Keep in Mind Some Effective Mosquito Repellents

Keep in Mind Some Effective Mosquito Repellents

Creams that help keep mosquitoes away usually contain active ingredients such as DEET, picaridin, and oil of lemon eucalyptus (OLE or the synthetic version PMD). Those ingredients are all endorsed by the U.S. Centers for Disease Control and Prevention as safe and effective in repelling insects, including mosquitoes. 


According to many experts, both DEET and picaridin are safe for anyone from two years old and up. To reduce bites from mosquitoes, which can carry diseases like malaria, dengue, and Zika, the CDC suggests choosing a cream with a DEET concentration of more than 20 percent


A picaridin concentration of about 20 percent also provides you with great protection against mosquitoes. Oil of lemon eucalyptus is another great ingredient that can effectively repel mosquitoes. However, it's advised to not use this ingredient for children under three years old as it can irritate their delicate skin. 

Dr. Lauren Levy
Board Certified Dermatologist
Dr. Lauren Levy

Insect repellants are highly effective at preventing bites. I recommend using DEET while outside to prevent bites. Do not forget to spray your lower legs and feet, which are prone to bites.

Frequently Asked Questions

In addition to reviewing and commenting on our buying guide, Dr. Levy also took the time to answer some commonly asked questions about mosquito bites.

Does itching make mosquito bites worse?

Dr. Levy says, "Scratching a mosquito bite can cause more histamine to be released in the skin. Histamine is one of the substances that create inflammation and leads to itching. When you scratch, you cause more histamine to be released in the area of the bug bite. This leads to blood vessels becoming dilated and resulting in redness, swelling, and itching."

What stops mosquito bites from itching?

Dr. Levy explains, "Medications that can decrease inflammation in the skin, like corticosteroids, or prevent histamine release, like antihistamines, can help reduce the itch. Itching from a bite is caused by substances in the saliva from the mosquito. 


The saliva triggers an inflammatory reaction in the skin, which leads to substances being released that cause itch. Eventually, the saliva will dissipate, and your body's immune system will stop reacting to the bite."

How can I prevent mosquito bites?

"Bug spray and repellent is the best way to prevent getting bitten by mosquitos," Dr. Levy says. "Also, wearing clothes that cover your body when outside or in the woods helps. Some people suggest taking oral Vitamin B supplements to ward off mosquitos; however, studies do not support this claim."

Protect Yourself From Bugs Even More

There are many products that can help you keep pesky insects away so you can enjoy your summer outdoors. Check out our articles for suggestions. 

In Collaboration With Board Certified Dermatologist Dr. Lauren Levy

Dr. Lauren Levy
Board Certified Dermatologist
Dr. Lauren Levy

This expert reviewed the contents of the buying guide for accuracy and provided factual corrections when necessary, as well as extra tips and advice. They did not participate in the product selection process, nor are they affiliated with any of our choices unless explicitly stated so.

Author: Thuy Nguyen


  • Follow us on Facebook and Instagram for more mybest recommendations! For questions or comments, leave us feedback via a Google Form on our Contact Us page.

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