10 Best Dog Flea and Tick Medicines in 2022 (Simparica, Sentinel, and More)

Simparica Trio chewable tablets have a pleasant liver taste and tackle a number of parasitic infections. When taken monthly, the tablets prevent heartworm disease, fleas, ticks, roundworms, and hookworms.

Dogs eight weeks or older can take the medication, and it comes in different weight ranges, from 2.8 to 132 pounds. You will need a prescription to get these tablets for your best friend.

A few reviewers complained that the tablets were not soft enough to be chewed and that their dogs would not take them without being disguised in food.

More buyers liked the convenience of only having to feed their dogs one medicine each month. They appreciated that the tablet provided protection against several types of diseases, saying it was a very convenient solution for different problems.

Sentinel flavor tablets prevent flea eggs from developing, along with heartworm disease, whipworms, roundworms, and hookworms. This medication is taken with food each month. It's available for dogs four weeks or older that are between two and 100 pounds.

Some buyers were disappointed that the product did not treat existing fleas or prevent ticks. They found they had to use topical medication alongside these tablets.

On the other hand, most reviewers noted their dogs seemed to enjoy the taste of the tablets and didn't need much coaxing to eat them. They liked that the tablets provided protection against several problems. A few noted that dogs with a history of seizures tolerated the medication.

This is a medication you apply on the back of your dog's shoulder and tail. The treatment can be used on dogs seven weeks or older. It works by killing and repelling ticks, mosquitoes, and fleas. The medication is waterproof and starts to work within 12 hours of application.

Some reviewers experienced that the medication didn't catch all ticks and fleas, especially in areas where they were abundant. That's why this product might be better paired with another option for full protection.

However, the great majority of reviewers praised the product. They said it was easy to apply and not too greasy. Many reported that their dogs stopped scratching after getting this treatment.

Frontline Plus offers protection against fleas, ticks, and lice. The treatment also kills eggs and larvae. It's applied between the dog's shoulders and gets absorbed into the skin. Frontline Plus is safe to use on dogs eight weeks of age and older.

Some reviewers reported receiving counterfeit products. Make sure when yours arrive to check that the medication is authentic. Reviewers who got the real deal, on the other hand, said it worked wonders against fleas and ticks. Some noted that it's a good option for small dogs.

Capstar's tablets are designed to kill fleas that currently exist on your dog. The tablets are taken each day until the infestation is gone. They don't prevent fleas, but they start working on existing ones within 30 minutes. The medication is safe for dogs that are four weeks or older. Tablets are available for dogs between two and 125 pounds.

Some reviewers noted that the tablets only works to kill adult fleas, and not eggs or hatched larvae. Luckily, many reviewers praised the medication and said it worked well to get rid of fleas on their dogs.

Fiproguard fights fleas, ticks, and chewing lice with fipronil. This is the top ingredient backed by many vets for flea and tick control. The medication is applied between your dog's shoulder blades. Fiproguard protects against brown, American, lone star, and deer ticks.

Some reviewers noted their dogs seemed to have an allergic reaction to the product. Their dogs experienced increased skin irritation and itching, so you might want to do a patch test before applying completely.

Still, a large number of reviewers appreciated this medication, saying it worked well on their dogs. Some even used it on their cats! This was a great option for preventing and treating fleas during different seasons.

This dog flea and tick medicine is approved by the FDA and will kill adult fleas and black-legged ticks on medium and large dogs. This is especially helpful since the latter can cause Lyme disease, which can be fatal. The tablets are chewable and taste like beef. They are safe for dogs aged eight weeks or older.

A few dogs reacted poorly to this medication, so read the side effects carefully before you give it to your pup. Some had upset stomachs or seizures. However, the majority of buyers said their dogs liked the flavor of the medicine, so it was easy to give to them. It also worked fast and was reliable in preventing fleas each month.

This preventative soft chew kills off ticks and fleas, including lone star ticks. Instead of giving your dog medication each month, you can wait three months in between chews. This medication should not be given to dogs with a seizure history or neurological issues.

A small number of dogs didn't like the taste of this medication and it was hard for a few reviewers to get them to eat it. However, most reviewers recommend the tablet for preventing and getting rid of fleas. They found it incredibly convenient that they only had to administer it every three months.

These tablets help treat current flea infestations and prevent new ones. The medicine can be given to dogs that are 14 weeks or older. Dogs can take the tablets with food each month, but breeding female dogs should not receive the medicine.

A few reviewers complained that their dogs did not like the strong smell of the tablet and it was difficult to get them to take it. However, many reviewers found long-term success with this product. It was able to prevent fleas for years. They liked feeling confident their dogs were protected while outside in grassy or humid areas.

This flea and tick collar makes it easy to use a topical solution to protect your dog. It can last up to seven months and repels and kills fleas, eggs, ticks, and larvae. The collar has reflective material for added safety and is safe to use on dogs 12 weeks of age or older.

Some reviewers noted that their dogs had allergic reactions to the collar or that it caused redness and loss of fur. On the other hand, a lot of reviewers were happy with the collar, saying it kept their dogs flea-free. Many also appreciated that it was reflective since it helped keep their dogs safe.