Top 10 Best Ergonomic Mouse in 2021 (Logitech, Razer, and More)

This mouse is great for both casual computer users and those whose professional lives require peak precision and productivity. The accompanying app for the mouse allows you set app-specific settings, which can come in handy for gamers, creatives, and professionals. 

Some reviewers said when using the free scroll mode, the mouse would go through pages very quickly, which was annoying for some reviewers. Those with small hands may also find the mouse a bit too big.

Most reviewers found the mouse comfortable for general use. Some even commented that the mouse felt like an extension of their hand, and reviewers with carpal tunnel were able to use the mouse for long periods of time with no pain. 

For fans of the trackball mouse, this ergonomic one has some added bells and whistles, such as a hinge to adjust the angle of the trackball from zero to 20 degrees, cross-computer use, and multiple-computer connectivity. 

Using the related software, you can also customize the buttons, and the battery is long-lasting, boasting four months of use with one full charge. 

Although many reviewers are big fans of this mouse, some found that the trackball picked up dirt easily, which meant cleaning the mouse daily. However, reviewers loved the quality and pain relief they got from the mouse, as well as the ability to seamlessly switch between devices using the mouse. 

This mouse is made by the first company to introduce the idea of the ergonomic mouse. Design details like the wide lip to prevent fingers from rubbing on the desk make this mouse a comfortable, practical option for making the time you spend on the computer as pain-free as possible. 

Some reviewers felt that the tracking precision on the mouse could be better. The accompanying software allows for button customization but is only compatible with Windows 7 and 10 and Mac OS 10.5 to 10.14. 

Reviewers who have recently had to spend more time on the computer experienced significant pain relief and are able to use their computers for long periods of time without problems in their wrists or hands. And good news for lefties: Evoluent has left-handed mouse options available as well! 

This vertical ergonomic mouse requires less hand movement than traditional mice due to the high 4000 DPI. There are three different ways to connect the mouse to the computer, and like the other Logitech mice on the list, it can jump across multiple computers. 

Some reviewers wished the mouse had a free-scrolling wheel for scrolling through long documents. Some with large hands also found the mouse too small. 

Reviewers found this mouse to be great for working because of the customization of the buttons. Others commented that the battery lasts a long time, and having the option to use the mouse with a wire was appreciated. 

This vertical ergonomic mouse comes with a detachable palm rest and blue LED light trim so you can see your mouse in the dark. The DPI is adjustable between 800, 1200, and 1600 so you can customize how precise and sensitive your mouse is. It also comes in a smaller version for those with small hands.

According to reviewers, those who need extremely precise movements, whether it's for games or work, may find this mouse to be insufficient. Some also said the scroll wheel sticks.

However, most enjoyed how easily they could use the mouse. Reviewers were happy with how much the mouse decreased their pain and found that they were able to be on the computer for full workdays without feeling any strain or tension. 

Despite being wireless, this mouse competes with the speeds of wired mice by reducing interactions with low frequencies and interferences. Many aspects of this ergonomic mouse are customizable, such as the 11 buttons, the color of the mouse, and scroll resistance. 

Some users do not like the software you need for full functionality. Other reviewers had the battery die on them too quickly, but there is a charging cord that comes from the dock that allows you to charge the mouse while using it. 

Reviewers found the mouse to be precise and smooth to use. Some reviewers stated that the mouse moves with the same speed and accuracy as wired mice, so they found it to be a comparable wireless option. 

With five adjustable DPI levels, the highest being 10,000 DPI, this mouse is perfect for gamers or those who work with high resolutions. The RGB lights on the mouse will change color depending on the level of sensitivity you set, making it easy to know what DPI the mouse is at. 

The joystick was hit or miss depending on the reviewer, but some said it was in an awkward place. Many reviewers were satisfied with the ergonomics of the mouse and the response of the buttons. They were shocked with how comfortable the mouse was to use and couldn't imagine going back to a traditional mouse. 

Finally, an ergonomic mouse for left-handed people or those trying to give their right hands a break! This L-shaped ergonomic mouse has six buttons and a spot under the mouse to store the USB that wirelessly connects the mouse to the computer. It comes in a wired version too.

Some reviewers found the mouse to be too vertical, which resulted in uncomfortable mouse use. Reviewers who were able to get used to switching to an ergonomic mouse experienced less arm, wrist, and hand pain. Getting the mouse set up is as easy as putting batteries in the mouse and plugging in the USB, according to reviewers. 

The benefits of an ergonomic mouse seem great until you can't find a mouse that is the right size for your small hands. Luckily, this mouse is designed specifically for people with small hands so that you can also reap the benefits of the ergonomic mouse. 

Some reviewers had connectivity problems with the mouse and found that having a clear path between the USB and mouse helped mitigate some of those issues. Others found it to start acting up or not responding properly after a few months. 

For basic, everyday use, reviewers found the mouse worked smoothly and felt comfortable. Many preferred the mouse over other mice they had or a trackpad. Reviewers with kids found the mouse to work for children as well. 

With a vertical design, this wireless mouse keeps your hand in a neutral position to alleviate strain and keep your desk free from clutter. There is also an option to adjust the mouse sensitivity, with choices of 800, 1200, or 1600 DPI for those that need their mouse to be able to do precision work. 

Some reviewers found the mouse flimsy and said the build quality was low. They complained that it developed glitches or just broke.

But even some of those same reviewers found the mouse helped alleviate their wrist pain and made their time on the computer more comfortable overall. People who spend upwards of eight to 10 hours a day on the computer loved the relief the mouse provided them in their wrists, hands, and fingers.